Viruses More Friends Than Foes Revised Edition

Author: Karin Moelling
Editor: World Scientific
ISBN: 9811224765
File Size: 50,67 MB
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Coronavirus, AIDS, and Ebola: Viruses are normally defined as pathogens. Most viruses are, however, not enemies or killers. Well-known virologist and cancer researcher Karin Moelling describes surprising insights about a completely new and unexpected world of viruses. Viruses are ubiquitous, in the oceans, our environment, in animals, plants, bacteria, in our body, even in our genomes. They influence our weather, can contribute to control obesity, and can surprisingly be applied against threatening multi-resistant bacteria. The success story of the viruses started more than 3.5 billion years ago in the dawn of life when even cells did not exist. They are the superpower of life. There are more viruses on earth than stars in the sky. Viruses are everywhere. Some of them are incredibly ancient. Many viruses are hundredfold smaller than bacteria, but others are tenfold bigger and they were discovered only recently — the giant viruses, even deep within the permafrost where they were reactivated after 30,000 years.The author talks about a completely new world of viruses, which are based on the most recent, in part her own research results. Could viruses have been our oldest ancestors? Have viruses even 'invented' social behavior, do they lead to geniuses such as Mozart or Einstein — or alternatively to cancer? They can help to cure cancer. In this book, the author made a clear distinction between what is fact and what is her vision. This book is written for a general audience and not just for the experts. Its aim is to stimulate thinking, and perhaps to attract more young scientists to enter this field of research.This revised edition is brought up to date by a new chapter on the SARS-CoV-2 pandemic.

Viruses

Author: Karin Moelling
Editor:
ISBN: 9789811227578
File Size: 28,66 MB
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Reviews of the Previous Edition: "Her style is chatty, and just when you want to break into the conversation and ask a question, she's thrown in an aside about a spat at a scientific meeting or discussed how we should dispose of our tissues when we have a cold. If this sort of mental gymnastics on top of some heavyweight science doesn't put you off, you'll like her book and learn much from it." Times Higher Education "Moëlling uses her successful career in the discipline to structure much of the book and includes numerous interesting personal anecdotes to underscore her points. The writing style is conversational and will be accessible to non-scientists. " CHOICE connect Reviews of the German edition: "The author describes a real success story of viruses which is fascinating and unconventional. What is presented with respect to knowledge, personal evaluations, amusing anecdotes from everyday life in research, is impressive." Neue Zurcher Zeitung, Zurich "I find your book excellent, instructive, and yet very entertaining." Emeritus Professor Charles Weissmann The Scripps Research Institute, Florida "Very amusing are the descriptions of the author's personal experiences with contemporary famous scientists. Rich with facts, this book is very worth reading also for non-specialists who would get to know the abundance of non-pathogenic viruses." Biology in Our Time Coronavirus, AIDS, and Ebola: Viruses are normally defined as pathogens. Most viruses are, however, not enemies or killers. Well-known virologist and cancer researcher Karin Moelling describes surprising insights about a completely new and unexpected world of viruses. Viruses are ubiquitous, in the oceans, our environment, in animals, plants, bacteria, in our body, even in our genomes. They influence our weather, can contribute to control obesity, and can surprisingly be applied against threatening multi-resistant bacteria. The success story of the viruses started more than 3.5 billion years ago in the dawn of life when even cells did not exist. They are the superpower of life. There are more viruses on earth than stars in the sky. Viruses are everywhere. Some of them are incredibly ancient. Many viruses are hundredfold smaller than bacteria, but others are tenfold bigger and they were discovered only recently -- the giant viruses, even deep within the permafrost where they were reactivated after 30,000 years. The author talks about a completely new world of viruses, which are based on the most recent, in part her own research results. Could viruses have been our oldest ancestors? Have viruses even "invented" social behavior, do they lead to geniuses such as Mozart or Einstein -- or alternatively to cancer? They can help to cure cancer. In this book, the author made a clear distinction between what is fact and what is her vision. This book is written for a general audience and not just for the experts. Its aim is to stimulate thinking, and perhaps to attract more young scientists to enter this field of research. This revised edition is brought up to date by a new chapter on the SARS-CoV-2 pandemic.

Plagued

Author: John Froude
Editor: BenBella Books
ISBN: 1953295363
File Size: 32,65 MB
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From the Black Death to Covid-19, pandemics have shaped and reshaped human society. Science and history can give us insight into two urgent questions: Why do they persist? And how can we survive them? Pandemics have been with us since Homo sapiens appeared on earth nearly 300,000 years ago. Forty percent of our genes are made of DNA from viruses. Yet we still remain vulnerable. Today, we are engulfed by a new pandemic: SARS-CoV-2 or the coronavirus that originated in China and, within four months, had spread to every country in the world. Thanks to advances in molecular biology and new tools with which to probe them, we are also in the midst of a golden age of understanding when it comes to our tiniest enemies. DNA technology is rewriting history, resolving disputes that have persisted for decades—and giving us crucial insights that may safeguard our future. Infectious Disease Specialist Dr. John Froude has worked on four continents over nearly 50 years, treating sufferers of plagues that arose over a century ago and never left us (like malaria and cholera) and battling new threats (like AIDS and Covid-19) as they emerge. In Plagued, he offers a gripping and timely account of the pandemics that have driven our evolution and shaped our history. Plagued tells the stories of yellow fever, smallpox, syphilis, the bubonic plague, influenza, typhus, cholera, malaria, tuberculosis, AIDS, and Covid-19. Blending science and narrative, Froude explores not only the unstoppable march of pestilence and its effects, but our intimate relationship with bacteria and viruses. He also explores the complex wonder that is human immunity, which itself is the consequence of an arms race between microbes and our animal ancestors that started 3.5 billion years ago. Along the way, we meet the dogged geniuses who have brought us back from the brink and see what it might take to do it again. Plagues arise without warning. But as we watch the current cataclysm unfold in real time, we have a unique opportunity to forge a path ahead that avoids both denial and panic. This timely book illustrates how lessons from the past, both distant and recent, may be the key to understanding why pandemics continue to plague us, and what can be done to stop them.

Viral Shapeshifters

Author: Gerard KM Goh
Editor: Simplicity Research Institute
ISBN: 9811147140
File Size: 60,42 MB
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Despite billions of dollars spent on decades of research, no vaccine has been found for the deadly HIV. Why has it been so difficult to find an effective vaccine for HIV, or the herpes simplex virus-2, while we have managed to find those for rabies, polio and smallpox? After years stalking the HIV and other viruses with a computer, the author detected something very strange in the outer shell protein of HIV-1. He believes that the virus is literally acting as a shapeshifter in evading the host immune system. This book is about a scientific adventure that covers the HIV, SARS, Yellow Fever, Ebola and other viruses. As this book explains, each virus has its own story in terms of evolution and its interactions with humans. It also argues that early vaccine successes with the smallpox, rabies and polio viruses were due to the hard shells of those viruses. The concept of viral shapeshifting also opens up a new world of possibilities in improved treatments for cancers and infectious diseases. The presentation in this book is aimed both at the curious layman and researchers.

Extremophiles As Astrobiological Models

Author: Joseph Seckbach
Editor: John Wiley & Sons
ISBN: 1119593115
File Size: 70,50 MB
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The data in this book are new or updated, and will serve also as Origin of Life and evolutionary studies. Endospores of bacteria have a long history of use as model organisms in astrobiology, including survival in extreme environments and interplanetary transfer of life. Numerous other bacteria as well as archaea, lichens, fungi, algae and tiny animals (tardigrades, or water bears) are now being investigated for their tolerance to extreme conditions in simulated or real space environments. Experimental results from exposure studies on the International Space Station and space probes for up to 1.5 years are presented and discussed. Suggestions for extaterrestrial energy sources are also indicated.

Handbook Of Astrobiology

Author: Vera M. Kolb
Editor: CRC Press
ISBN: 1351661108
File Size: 47,60 MB
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Read an exclusive interview with Professor Vera Kolb here. Astrobiology is the study of the origin, evolution, distribution, and future of life on Earth. This exciting and significant field of research also investigates the potential existence and search for extra-terrestrial life in the Solar System and beyond. This is the first handbook in this burgeoning and interdisciplinary field. Edited by Vera Kolb, a highly respected astrobiologist, this comprehensive resource captures the history and current state of the field. Rich in information and easy to use, it assumes basic knowledge and provides answers to questions from practitioners and specialists in the field, as well as providing key references for further study. Features: Fills an important gap in the market, providing a comprehensive overview of the field Edited by an authority in the subject, with chapters written by experts in the many diverse areas that comprise astrobiology Contains in-depth and broad coverage of an exciting field that will only grow in importance in the decades ahead

Dengue Fever In A One Health Perspective

Author:
Editor: BoD – Books on Demand
ISBN: 1789852021
File Size: 76,75 MB
Format: PDF
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Dengue Fever in a One Health Perspective underlines important aspects of dengue virus, the most prevalent and life-threatening arbovirus in the world. Over three sections, chapters cover such topics as biological and environmental aspects, physiopathology, molecular biology, diagnosis, and control strategies. The first section provides knowledge on basic aspects of dengue virus biology and its emergence and re-emergence associated to environmental changes. The second section includes two chapters on dengue immunopathology, a drawback in disease control and vaccine development. Finally, the third section examines molecular biology tools employed in dengue virus immunopathogenesis studies, diagnosis, drug design, and in the use of vectors as sentinels in surveillance and vector biology studies.

Plant Physiological Aspects Of Phenolic Compounds

Author: Marcos Soto-Hernández
Editor: BoD – Books on Demand
ISBN: 1789840333
File Size: 28,38 MB
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Phenolic compounds are considered secondary metabolites within the physiology of a plant. They have different functions, such as pollination systems, sun protection, protection against pathogens and diseases, etc.Research on these compounds has increased due to the number of molecules they can include and the different biological activities they demonstrate. It is important to know the methods of extracting molecules, the biosynthesis routes, and their relationship with activities that can benefit from their consumption. Therefore, the book includes chapters that provide information on extraction and optimization techniques, biosynthetic pathways, and the identification and characterization of miRNAs involved in the regulation of their biosynthesis.

Genome Invading Rna Networks

Author: Guenther Witzany
Editor: Frontiers Media SA
ISBN: 2889454770
File Size: 31,24 MB
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A new paradigmatic understanding of evolution, genetic novelty, code-generating, genome-formatting factors, infectious RNA Networks, viruses and other natural genetic content operators.

Integrative Genomics And Network Biology In Livestock And Other Domestic Animals

Author: David E. MacHugh
Editor: Frontiers Media SA
ISBN: 2889639991
File Size: 40,86 MB
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Chasing Life

Author: Sanjay Gupta
Editor: Hachette UK
ISBN: 0446195006
File Size: 32,13 MB
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For centuries, adventurers and scientists have believed that not only could we delay death but that "practical immortality" was within our reach. Today, many well-respected researchers would be inclined to agree. In a book that is not about anti-aging, but about functional aging--extending your healthy, active life--Dr. Sanjay Gupta blends together compelling stories of the most up-to-date scientific breakthroughs from around the world, with cutting-edge research and advice on achieving practical immortality in this lifetime. Gupta's advice is often counterintuitive: longevity is not about eating well, but about eating less; nutritional supplements are a waste of your money; eating chocolate and drinking coffee can make you healthier. Chasing Life tells the stories behind the breakthroughs while also revealing the practical steps readers can take to help extend youth and life far longer than ever thought possible.

Why We Hurt

Author: Frank T. Vertosick
Editor: Mariner Books
ISBN: 9780156014038
File Size: 53,44 MB
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Using stories of patients in pain, a neursurgeon and author of When the Air Hits Your Brain explains how pain evolved and why it functions the way it does, providing a mixture of medicine, history, anthropology and inspiration. Reprint. 20,000 first printing.

Natural Killer Cells In Human Diseases Friends Or Foes

Author: Vincent Vieillard
Editor: Frontiers Media SA
ISBN: 2889454045
File Size: 33,96 MB
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NK cells are lymphocytes of the innate immune system that share some features with adaptive immune cells like T cells. They are well known for their importance to control viral infections and tumor development, but also intracellular bacterial and parasitic infections. A balance between negative and positive signals transmitted via germ line-encoded inhibitory and activating receptors controls the function of NK cells. Activated NK cells respond by killing the infected or tumor cells without prior sensitization, and by producing cytokines and chemokines. It has been shown that NK cells cross-talk with other immune cells, such as dendritic cells and macrophages, can shape T cell and B cell immune responses through direct interactions as well as by virtue of their cytokine/chemokine production. NK cells can also regulate immune responses by killing other immune cells, including activated T cells, or by producing anti-inflammatory cytokines upon excessive inflammation. However, NK cells are not friends in all situations. Indeed, it has been shown in LCMV-infected murine models that, depending on the viral inoculation load, NK cells may either help fight infection or can promote chronic infection. Moreover in cancer models, it has been shown that NK cells can kill anti-tumoral T cells. Recent studies of NK cells in patients with cancer support the notion of detrimental roles of NK cells. Furthermore, studies implicate NK cells in contributing to both graft rejection and tolerance to an allograft. In some autoimmune diseases, like rheumatoid arthritis, NK cells may promote disease pathogenesis. The scope of this Research Topic is to present and discuss knowledge on the role of NK cells in various diseases settings: viral infections as well as other infections, cancer, transplantation, and autoimmunity. The aim is to discuss how NK cells respond during disease and specifically when, why and how NK cells can be harmful and if they exert different functions (production of specific cytokines, inhibition of other immune cells through other mechanisms beside cytotoxicity) in these situations. Which are the NK cell subsets that play beneficial or deleterious roles in these diseases? Are there different phenotypes associated with protective NK cells (e.g. antiviral, antitumoral) and NK cells involved in disease pathogenesis? How are these diverse NK cells activated and do they function primarily through direct cytotoxicity, ADCC or cytokine and chemokine production? What are the signals or interactions that can change and shape the NK cell response shifting them from protective to harmful? We thank the authors that submitted reviews and original research manuscripts that help to better understand these questions, with the aim that this will help the scientific community to determine what could be the main future research directions to better understand the role of NK cells in disease protection or development.

New Zealand Journal Of Agriculture

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Editor:
ISBN:
File Size: 36,32 MB
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Longman Active Science 8

Author: Narayanan Vidhu
Editor: Pearson Education India
ISBN: 9788131728420
File Size: 31,99 MB
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Actes

Author:
Editor:
ISBN:
File Size: 41,50 MB
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Old Friends New Enemies

Author: Theresa Snyder
Editor: Theresa Snyder
ISBN:
File Size: 16,14 MB
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It has been thirty years since Jake and Arr settled down and gave up the mercenary trade. Arr's life is falling apart. During a spice delivery to Gamma 12 Jake's life is threatened. At the same time in a distant corner of the Rigil galaxy Arr's daughter and her partner are thrust into a situation where they must depend on each other in order to survive, but they may need Dad's help to get through their ordeal. Meanwhile, Targus has lost Damion Mitchell to retirement. Targus' search for a new medical officer for his crew leads him to a newly graduated Galactic Forces Academy officer, Terrell Sterling. Terrell has an unexpected connection to the Henu and enough personal baggage to choke a Tuldavian Swamp Lizard. All three plots collide in a spectacular finale that will leave you seeking more Star Traveler adventures.

In A World Of Friends Foes Fools

Author: James Merritt
Editor: Xulon Press
ISBN: 1606476009
File Size: 48,31 MB
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One of the wisest men who ever lived is writing a letter of advice to his children, and you can look over his shoulder. The Proverbs of Solomon take on a new meaning when read as a letter from father to son. The advice of the wise old king is invaluable to today's fathers struggling with the pressures of home and career responsibilities, travel, broken families and other realities of modern life. In Friends, Foes and Fools, Dr. James Merritt shows why no book ever written has been a better or more practical self-help guide than Proverbs in helping fathers guide their children toward the right choices in life, and away from the wrong ones. "Dad, if you want to read a book that will change you and your family, read this one!" Dr. John C. Maxwell Founder, INJOY Dr. James Merritt is the Senior Pastor and Founder of Cross Pointe, The Church at Gwinnett Center, located in Duluth, Georgia, and hosts the international broadcast ministry, Touching Lives, which airs in all 50 states and in 122 countries around the world. The ministry also reaches literally every continent through the world-wide web at www.touchinglives.org. Dr. Merritt and his wife, Teresa, reside just outside Atlanta, Georgia.

Treasury Of Home Remedies

Author: Myra Cameron
Editor: Prentice Hall Direct
ISBN: 9780139306372
File Size: 66,10 MB
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Suggests herbs for alleviating common ailments from acne, allergies, and athlete's foot to ulcers, warts, and wounds

Epistemology Of The Closet

Author: Eve Kosofsky Sedgwick
Editor: Univ of California Press
ISBN: 0520254066
File Size: 78,67 MB
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Since the late 1980s, queer studies and theory have become vital to the intellectual and political life of the United States. This has been due, in no small degree, to the influence of Eve Kosofsky Sedgwick's critically acclaimed Epistemology of the Closet. Working from classic texts of European and American writers—including Melville, James, Nietzsche, Proust, and Wilde—Sedgwick analyzes a turn-of-the-century historical moment in which sexual orientation became as important a demarcation of personhood as gender had been for centuries. In her preface to this updated edition Sedgwick places the book both personally and historically, looking specifically at the horror of the first wave of the AIDS epidemic and its influence on the text.